Ovidac 5000 IU
Human Chorionic Gonadotropin : it is a hormonal substance obtained from human pregnancy urine . in the female , its action is predominantly luteinizing. In the male , its action is predominantly steridogenic and can also initate and maintan spermatogensis.
Indications :in female : Anovulatory infertility superovulation for an assisted conception- technique. Corpus luteum insuffi-ciency. Habitual abortion . threatened abortion. In male :hypogonadotrophic hypogonadism. Cryptorchidism. Oligoasthenospermia and azoospermia.
Dosage: Anovulatory infertility & superovulation: 10,000i.u.corpus iuteum insufficiency: 5,000 i.u. on th day after ovulation repeated on 9th day . habitual & threatened abortion : 10,000 i.u. followedby 5,000 i.u. twice weekly .
Male : Hyppogonadotrphic hypogonadism : 2,000 i.u. twice weekly. Cryptochidism: 500-1,000i.u. on alternate day . oligo-asthenospermia & azoosper –mia 500i.u.every day 2,500 i.u. every 5 days.
Cotraindications: hypersensitivity. Pituitary or ovarian tumour , prostatic carcinoma or androgen dependent neoplasm. Endocrine disorders. Ovarian dys-genesis, absent uterus, premature menopause , tubal occlusion. Active thrombophlebitis. Weight reduction.
Special Precautions: Ovarian hyperstimulation syndrome. Incidence of multiple pregnancies & births is incressed. False result of pregnancy tes, breast feeding . in males may cause fluid retention ( caution in patients with cardiac , renal disease , epilepsy, migraine or asthma) . Sexual precocity.
Side-effects : Local reaction or pain at injection site . headache, tiredness, mental depression, irritability, restlessness. Ovarian hyperstimulation syndrome, oedema, gynaecomastia.
Drug Interactions: None known.